Publications

‪Kyle Lampe‬ - ‪Google Scholar‬ 

36. R Yokosawa, RA Mazur, KA Wilson, JH Lee, NW Showalter, KJ Lampe, PJ VandeVord, "High-Rate Mechano-Stimulation Alters Proliferation- and Maturation-Related Signaling of Oligodendrocyte Precursor Cells in a 3D Hydrogel," Mechanobiology in Medicine. (2025). LINK

35. RA Mazur, KJ Lampe, "Guiding Oligodendrocyte Progenitor Cell Maturation Using Electrospun Fiber Cues in a 3D Hyaluronic Acid Hydrogel Culture System," ACS Biomaterials Science & Engineering. (2025). LINK

34. AT Thede, JD Tang, CE Cocker, LJ Harold, CD Amelung, AR Kittel, PA Taylor, KJ Lampe, "Effects of Cell-Adhesive Ligand Presentation on Pentapeptide Supramolecular Assembly and Gelation: Simulations and Experiments," Cells Tissues Organs. (2023). LINK

33. I Jahan Duti, JR Florian, AR Kittel, CD Amelung, VP Gray, KJ Lampe+, RA Letteri+, “Peptide Stereocomplexation Orchestrates Supramolecular Assembly of Hydrogel Biomaterials,” Journal of the American Chemical Society, (2023). LINK
+co-corresponding authors

32. RK Ghanta, A Pugazenthi, Y Zhao, C Sylvester, MJ Wall, RA Mazur, LN Russell, KJ Lampe, "Influence of Supraphysiologic Biomaterial Stiffness on Ventricular Mechanics and Myocardial Infarct Reinforcement," Acta Biomaterialia. (2022). LINK

31. RA Mazur, R Yokosawa, PJ VandeVord, KJ Lampe, "The Need for Tissue-engineered Models to Facilitate the Study of Oligodendrocyte Progenitor Cells in Traumatic Brain Injury and Repair," Current Opinion in Biomedical Engineering. 22: 100378 (2022). LINK

30. VP Gray, CD Amelung, IJ Duti, EG Laudermilch, RA Letteri, KJ Lampe, "Biomaterials via Peptide Assembly: Design, Characterization, and Application in Tissue Engineering," Acta Biomaterialia. 140: 43-75 (2022). LINK

29. DB Unal, SR Caliari, KJ Lampe, "3D Hyaluronic Acid Hydrogels for Modeling Oligodendrocyte Progenitor Cell Behavior as a Function of Matrix Stiffness," Biomacromolecules. 21 (12), 4962-4971 (2020). LINK

28. E Meco, WS Zheng, A Sharma, KJ Lampe, "Guiding Oligodendrocyte Precursor Cell Maturation with Urokinase Plasminogen Activator-degradable Elastin-like Protein Hydrogels," Biomacromolecules. 21 (12), 4724-4736 (2020).Just accepted. LINK

27. DB Unal, SR Caliari, KJ Lampe, "Engineering Biomaterial Microenvironments to Promote Myelination in the Central Nervous System," Brain Research Bulletin.152:159-174 (2019). LINK

26. JD Tang, Roloson EB, Amelung CD, KJ Lampe, "Rapidly Assembling Pentapeptides for Injectable Delivery (RAPID) Hydrogels as Cytoprotective Cell Carriers," ACS Biomater. Sci. Eng. 5: 2117-2121 (2019) . LINK

25. E Meco, KJ Lampe, "Impact of Elastin-like Protein Temperature Transition on PEG-ELP Hybrid Hydrogel Properties," Biomacromolecules, 20, 5, 1914–1925 (2019). LINK

24. JD Tang, C Mura, KJ Lampe, "A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering," J. Am. Chem. Soc., 141: 4886-4899 (2019). LINK

23. CM Madl, BL LeSavage, RE Dewi, KJ Lampe & SC Heilshorn, "Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels," Advanced Science, 6: 1801716 (2019). LINK

22. JD Tang, SR Caliari, KJ Lampe, "Temperature-dependent complex coacervation of engineered elastin-like polypeptide and hyaluronic acid polyelectrolytes," Biomacromolecules, 19: 3925-3935 (2018). LINK

21. MR Pinezich, LN Russell, NP Murphy, KJ Lampe, “Encapsulated oligodendrocyte precursor cell fate is dependent on PDGF-AA release kinetics in a 3D microparticle-hydrogel drug delivery system,” Journal of Biomedical Materials Research-A, 106: 2402-2411 (2018). (LINK)

20. E Meco, KJ Lampe, "Microscale architecture in biomaterial scaffolds for spatial control of neural cell behavior," Frontiers in Materials, 5: 2 (2018). LINK

19. JD Tang, KJ Lampe, “From de novo peptides to native proteins: advancements in biomaterial scaffolds toward acute ischemic stroke repair,” Biomedical Materials, 13: 3 (2018). LINK

18. CM Madl, BL LeSavage, RE Dewi, CB Dinh, RS Stowers, M Khariton, KJ Lampe, DNguyen, O Chaudhuri, AEnejder & SC Heilshorn, "Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling," Nature Materials 16, 1233-1242 (2017). (LINK)

17. NP Murphy, KJ Lampe, “Fabricating PLGA microparticles with high loads of the small molecule antioxidant N-acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress,” Biotechnology and Bioengineering, 115: 246-256 (2017). LINK

16. LN Russell, KJ Lampe, "Oligodendrocyte Precursor Cell Viability, Proliferation, and Morphology is Dependent on Mesh Size and Storage Modulus in 3D Poly(ethylene glycol) Based Hydrogels," ACS Biomater. Sci. Eng. (2017). LINK

15. JD Tang, CE McAnany, C Mura, KJ Lampe, "Toward a Designable Extracellular Matrix: Molecular Dynamics Simulations of an Engineered Laminin-Mimetic, Elastin-Like Fusion Protein," Biomacromolecules, 17: 3222–3233 (2016). LINK

14. LN Russell, KJ Lampe, “Engineering biomaterials to influence oligodendroglial growth, maturation, and myelin production,” Journal of Cells, Tissues, and Organs, 202: 85-101 (2016).LINK

13. NP Murphy, KJ Lampe, “Mimicking biological phenomena in hydrogel-based biomaterials to promote dynamic cellular responses,” Journal of Materials Chemistry B, 3: 7867-7880 (2015). (LINK)

12. NH Romano, KJ Lampe, H Xu, MM Ferreira, SC Heilshorn “Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities,” Small, 11: 722-730 (2015). (LINK)

11. KJ Lampe, AL Antaris, SC Heilshorn “Design of 3D engineered protein hydrogels for tailored control of neurite growth,” Acta Biomaterialia, 9: 5590-5599 (2013). (LINK)

10. C Chung, KJ Lampe, SC Heilshorn “Tetrakis (hydroxyl methyl) phosphonium chloride as a covalent crosslinking agent for cell encapsulation within protein-based hydrogels,” Biomacromolecules, 13: 3912-3916 (2012). (LINK)

9. KJ Lampe, SC Heilshorn “Building stem cell niches from the molecule up through engineered peptide materials,” Invited review, Neuroscience Letters, 519: 138-146 (2012). (LINK)

8. BA Aguado, W Mulyasasmita, J Su, KJ Lampe, SC Heilshorn, “Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers,” Tissue Engineering Part A, 18: 806-815 (2012). (LINK)

7. ER Aurand, KJ Lampe, KB Bjugstad, “Defining and Designing Polymers and Hydrogels for Neural Tissue Engineering,” Neuroscience Research, 72: 199-213 (2012). (LINK)

6. KJ Lampe, DS Kern, MJ Mahoney, KB Bjugstad, “The administration of BDNF and GDNF to the brain via PLGA microparticles patterned within a degradable PEG-based hydrogel: protein distribution and the glial response,” Journal of Biomedical Materials Research Part A, 96A: 595-607 (2011). (LINK)

5. KB Bjugstad, KJ Lampe, DS Kern, MJ Mahoney, “Biocompatibility of poly(ethylene glycol)-based hydrogels in the brain: An analysis of the glial response across space and time,” Journal of Biomedical Materials Research Part A, 95A:79-91 (2010). (LINK)

4. KJ Lampe*, RG Mooney*, KB Bjugstad, MJ Mahoney, “Effect of macromer weight percent on neural cell growth in 2D and 3D nondegradable PEG hydrogel culture,” Journal of Biomedical Materials Research Part A: 94A, 1162-1171 (2010). (LINK) *contributed equally to this work

3.KJ Lampe, KB Bjugstad, MJ Mahoney, “Impact of degradable macromer content in a poly(ethylene glycol) hydrogel on neural cell metabolic activity, redox state, proliferation, and differentiation,” Tissue Engineering Part A, 16:1857-1866 (2010). (LINK)

2. KJ Lampe, RM Namba, TR Silverman, KB Bjugstad, MJ Mahoney, “Impact of lactic acid on cell proliferation and free radical-induced cell death in monolayer cultures of neural precursor cells,” Biotechnology and Bioengineering, 103:1214-1223 (2009). (LINK)

1. KB Bjugstad, DE Redmond, KJ Lampe, DS Kern, JR Sladek Jr, MJ Mahoney, “Biocompatibility of PEG-Based Hydrogels in Primate Brain,” Cell Transplantation, 17:409-417 (2008). (LINK)